منابع مشابه
4 Esteban Rodriguez N45-3.indd
Most cells of the developing mammalian brain derive from the ventricular (VZ) and the subventricular (SVZ) zones. The VZ is formed by the multipotent radial glia/neural stem cells (NSCs) while the SVZ harbors the rapidly proliferative neural precursor cells (NPCs). Evidence from human and animal models indicates that the common history of hydrocephalus and brain maldevelopment starts early in e...
متن کامل6 Francisco Rivera N45-3.indd
Multiple sclerosis (MS) is a demyelinating immune-mediated disease of the central nervous system (CNS). It is the most frequent neurological disease in young adults and aff ects over 2 million people worldwide. Current treatments reduce the relapse rate and the formation of infl ammatory lesions in the CNS, but with only temporary and limited success. Despite the presence of endogenous oligoden...
متن کامل8 Ana Maria Pino N45-3.indd
The formation, maintenance, and repair of bone tissue involve close interlinks between two stem cell types housed in the bone marrow: the hematologic stem cell originating osteoclasts and mesenchymal stromal cells (MSCs) generating osteoblasts. In this review, we consider malfunctioning of MSCs as essential for osteoporosis. In osteoporosis, increased bone fragility and susceptibility to fractu...
متن کامل10 Enrique Castellon N45-3.indd
Prostate cancer (PCa) is the most frequently diagnosed malignancy in men worldwide. Chemotherapy response is very poor and resistance to hormone-based treatments is frequent in advances stages. Recently, tumor-initiating cells or cancer stem cells (CSCs) have been identifi ed in several cancers, including PCa. These cells are thought to be responsible for therapy resistance, relapse and metasta...
متن کامل7 Fernando Figueroa N45-3.indd
Mesenchymal stem cells (MSCs) are now known to display not only stem cell multipotency, but also robust antiinfl ammatory and regenerative properties. After widespread in-vitro and in-vivo preclinical testing, autologous and allogeneic MSCs have been applied in a range of immune mediated conditions, including graft versus host disease, Crohn ́s disease, multiple sclerosis, refractory systemic lu...
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ژورنال
عنوان ژورنال: Revista Profissão Docente
سال: 2020
ISSN: 1519-0919
DOI: 10.31496/rpd.v20i45.1396